AGIO — AGIOS PHARMACEUTICALS, INC.

Nasdaq · Health Care · Pharmaceuticals · CIK 1439222 ·
Last close
$30.02
Market Cap
$1.79B
52W High
$44.09
52W Low
$26.44
ADV30
1,285,097
Next earnings
2026-10-29
Agios Pharmaceuticals, Inc., a biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. Its lead product includes PYRUKYND (mitapivat), an activator of wild-type and mutant pyruvate kinase (PK), enzymes used for the treatment of hemolytic anemias in adults with PK deficiency. The company's PYRUKYND product is also used for the treatment of sickle cell disease that is in phase 3 clinical trial; for the treatment of PK deficiency in pediatric patients; and AQVESME for the treatment of adult patients with non-transfusion dependent and transfusion-dependent alpha- or beta-thalassemia. In addition, it developed tebapivat, a PK activator for the treatment of lower-risk myelodysplastic syndrome and sickle cell disease; AG-181, a phenylalanine hydroxylase stabilizer for the treatment of phenylketonuria (PKU); and AG-236, an siRNA in-licensed from Alnylam, targeting the transmembrane serine protease 6 (TMPRSS6) gene for the treatment of polycythemia vera. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Jun 2026 44,745,000 41,749,000 -110,552,000 -100,703,000 1,108,424,000 99,647,000 82,403,000
Mar 2026 20,746,000 19,427,000 -110,025,000 -99,111,000 1,184,990,000 113,600,000 75,875,000
Dec 2025 19,967,000 18,088,000 -121,578,000 -108,039,000 1,297,225,000 89,130,000 104,111,000
Sep 2025 12,880,000 11,201,000 -116,869,000 -103,433,000 1,385,705,000 92,710,000 101,375,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-360,596,000
Investing CF
$367,153,000
Financing CF
$12,219,000
CapEx
$-29,656,000
Dividends Paid
Buybacks
EPS Diluted TTM
$-7.09
As of
2026-08-02

Balance + Analyst (yfinance extras)

Retained Earnings
$-761,519,000
Inventory
$30,152,000
Receivables
$24,216,000
ST Investments
$517,929,000
EBIT TTM
$-459,024,000
Pretax Income TTM
$-412,302,000
Interest Exp TTM
Analysts
8

Yahoo Snapshot (yfinance, live)

Total Revenue
$98,338,000
EBITDA
$-453,671,008
Free Cash Flow
$-274,604,000
Enterprise Value
$1,205,845,504
Total Cash
$617,576,000
Total Debt
$31,171,000
Shares Out
59,701,882
Trailing EPS
$-7.01
Book Value
$20.41
ROE
-34.3%
ROA
-22.2%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 54,028,000 -472,132,000 -412,781,000 1,297,225,000 104,111,000 -372,977,000
Dec 2024 36,498,000 -425,737,000 673,725,000 1,663,199,000 122,243,000 -389,841,000
Dec 2023 26,823,000 -391,487,000 -352,088,000 937,118,000 126,099,000 -296,062,000
Dec 2022 14,240,000 -389,047,000 -231,801,000 1,238,718,000 137,904,000 -309,478,000

TTM Snapshot

Revenues TTM
$19,879,000
NetIncome TTM
$686,078,000
OpCashFlow TTM
$0
Assets (Latest)
$1,663,199,000
Forward EPS
$-4.30

Max Pain — expiry 2026-12-18

max pain strike: $25.00 · spot: $30.02 · call oi: 29,283 · put oi: 664
Expected Move to 2026-12-18: ±$9.60 (31.98%) — implied range $20.42$39.62 · ATM straddle on $30.00 strike

Peers — same industry

TickerNameMarket CapLastDaily %
GENB Generate Biomedicines, Inc. $1.79B $14.00
OCUL OCULAR THERAPEUTIX, INC $1.79B $8.17
STOK Stoke Therapeutics, Inc. $1.80B $28.86
DMRA Damora Therapeutics, Inc. $1.78B $28.99
ANIP ANI PHARMACEUTICALS INC $1.80B $79.24

News headlines (Yahoo Finance, 1h cache)

AGIO Q2 Earnings Beat Estimates, Revenues Increase Year Over Year
2026-07-31 16:17 · Yahoo
Agios Pharmaceuticals Inc (AGIO) (Q2 2026) Earnings Call Highlights: Strong Mitapivat Revenue ...
2026-07-30 19:02 · Yahoo
Agios Pharmaceuticals Q2 Earnings Call Highlights
2026-07-30 14:04 · Yahoo
Agios Pharmaceuticals (AGIO) Reports Q2 Loss, Beats Revenue Estimates
2026-07-30 11:50 · Yahoo
Agios Reports Second Quarter 2026 Financial Results and Provides Business Update
2026-07-30 10:30 · Yahoo
Tebapivat Sickle Cell Setback and Mitapivat Priority Review Could Be A Game Changer For Agios (AGIO)
2026-07-30 00:14 · Yahoo
The Zacks Analyst Blog Highlights Harmony Biosciences, Acadia Pharmaceuticals, Biogen, Insmed and Agios Pharmaceuticals
2026-07-28 08:58 · Yahoo
Watch These 5 Biotech Stocks for Q2 Earnings: Beat or Miss?
2026-07-27 16:36 · Yahoo
Neurocrine Gears Up to Report Q2 Earnings: What's in the Cards?
2026-07-27 15:11 · Yahoo
Agios Pharmaceuticals (AGIO) Expected to Beat Earnings Estimates: What to Know Ahead of Q2 Release
2026-07-23 14:00 · Yahoo

Recent Insider Activity

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