ANRO — Alto Neuroscience, Inc.

NYSE · Health Care · Pharmaceuticals · CIK 1999480 ·
Last close
$21.47
Market Cap
$753.47M
52W High
$28.44
52W Low
$17.90
ADV30
346,437
Next earnings
2026-08-12
Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States. The company's product pipeline includes ALTO-100, which is in Phase 2b clinical trial for the treatment of patients with bipolar depression (BPD). It also develops ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties, which is in Phase 2b clinical trial to treat patients with major depressive disorder (MDD); ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor that is in Phase 2 proof-of-concept (POC) trial for the treatment of cognitive impairment associated with schizophrenia; ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist, which is in Phase 2 POC trial to treat patients with MDD and higher levels of anhedonia; ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor that is in Phase 1 clinical trial for the treatment of MDD; and ALTO-208, a fixed-dose combination of pramipexole and aprepitant, an antiemetic, neurokinin-1 (NK-1) receptor antagonist for patients with Parkinson's disease for patients with Parkinson's disease. The company was incorporated in 2019 and is headquartered in Mountain View, California.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 0 -27,138,000 -26,237,000 276,259,000 263,762,000 32,890,000
Dec 2025 0 -17,055,000 -16,182,000 184,689,000 176,484,000 33,547,000
Sep 2025 0 -14,951,000 -14,181,000 147,006,000 137,816,000 35,449,000
Jun 2025 0 -18,682,000 -17,706,000 157,877,000 147,585,000 34,465,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-62,304,000
Investing CF
$-556,000
Financing CF
$165,892,000
CapEx
$-2,091,000
Dividends Paid
Buybacks
$-4,775,000
EPS Diluted TTM
$-2.53
As of
2026-06-07

Balance + Analyst (yfinance extras)

Retained Earnings
$-227,871,000
Inventory
Receivables
$0
ST Investments
EBIT TTM
$-71,890,000
Pretax Income TTM
$-74,306,000
Interest Exp TTM
$2,416,000
Analysts
11

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 0 -66,364,000 -63,238,000 184,689,000 33,547,000 -51,769,000
Dec 2024 0 -68,610,000 -61,431,000 177,542,000 26,082,000 -47,424,000
Dec 2023 0 -37,809,000 -36,305,000 86,628,000 158,300,000 -33,448,000
Dec 2022 0 -27,455,000 -27,710,000 50,854,000 89,260,000 -20,394,000

TTM Snapshot

Revenues TTM
$3,214,000
NetIncome TTM
$-25,924,000
OpCashFlow TTM
$0
Assets (Latest)
$177,542,000
Forward EPS
$-3.43

Max Pain — expiry 2026-07-17 (volume-derived — Yahoo OI feed degraded)

max pain strike: $30.00 · spot: $21.17 · call volume: 50 · put volume: 105
Expected Move to 2026-07-17: ±$7.37 (34.81%) — implied range $13.80$28.54 · ATM straddle on $20.00 strike

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ANNX Annexon, Inc. $771.70M $4.71

News headlines (Yahoo Finance, 1h cache)

Alto Neuroscience Highlights Nature Medicine Publication Demonstrating Significant Effects of Pramipexole on Anhedonia
2026-06-15 12:03 · Yahoo
Alto Neuroscience Appoints Karuna Therapeutics Founder Andrew Miller, Ph.D. to Board of Directors
2026-05-28 12:03 · Yahoo
Alpha Wave Global Initiates COPT Defense Properties Position, According to Recent SEC Filing
2026-05-27 05:19 · Yahoo
Alto Neuroscience CEO Amit Etkin, M.D., Ph.D. Receives Columbia University Transformational Research Award
2026-05-15 12:27 · Yahoo
Alto Neuroscience Reports First Quarter 2026 Financial Results and Recent Business Highlights
2026-05-13 11:03 · Yahoo
Alto Neuroscience Announces Participation in Upcoming Investor Conferences
2026-05-11 20:05 · Yahoo
Alto Neuroscience Presents Phase 2a Data for ALTO-207 in Major Depressive Disorder at SOBP Annual Meeting
2026-05-04 12:03 · Yahoo
Alto Neuroscience Initiates Phase 2b Trial of ALTO-207 in Treatment-Resistant Depression
2026-04-21 12:03 · Yahoo
Top 1% Alto Neuroscience Plummets On Its Shocking Schizophrenia Miss
2026-04-02 20:10 · Yahoo
Sector Update: Health Care Stocks Softer Late Afternoon
2026-04-02 19:57 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.