DNLI — Denali Therapeutics Inc.

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Nasdaq · Health Care · Biotechnology · CIK 1714899 ·
Last close
$20.39
Market Cap
$3.26B
52W High
$27.30
52W Low
$13.28
ADV30
1,415,917
Next earnings
2026-11-05

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGross profitOp incomeNet incomeAssetsCashLiabilities
Jun 2026 3,604,000 3,511,000 -130,541,000 -127,553,000 1,157,955,000 201,530,000 322,777,000
Mar 2026 0 — -137,357,000 -128,447,000 1,266,023,000 387,626,000 339,925,000
Dec 2025 0 — -137,365,000 -128,549,000 1,144,854,000 205,326,000 131,093,000
Sep 2025 0 — -137,434,000 -126,902,000 1,055,621,000 90,963,000 129,424,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-434,040,000
Investing CF
$68,980,000
Financing CF
$425,383,000
CapEx
$-37,873,000
Dividends Paid
—
Buybacks
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EPS Diluted TTM
$-2.84
As of
2026-08-09

Balance + Analyst (yfinance extras)

Retained Earnings
$-2,307,524,000
Inventory
$4,139,000
Receivables
$3,927,000
ST Investments
$508,941,000
EBIT TTM
$-542,697,000
Pretax Income TTM
$-511,349,000
Interest Exp TTM
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Analysts
16

Yahoo Snapshot (yfinance, live)

Total Revenue
$3,604,000
EBITDA
$-526,057,984
Free Cash Flow
$-268,527,872
Enterprise Value
$2,698,396,672
Total Cash
$710,470,976
Total Debt
$37,686,000
Shares Out
159,847,403
Trailing EPS
$-2.84
Book Value
$5.23
ROE
-54.9%
ROA
-29.1%
Div Yield
—

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOp incomeNet incomeAssetsLiabilitiesEquityOp cash flow
Dec 2025 0 -555,342,000 -512,540,000 1,144,854,000 131,093,000 1,013,761,000 -412,600,000
Dec 2024 0 -501,878,000 -422,773,000 1,374,180,000 144,496,000 1,229,684,000 -347,694,000
Dec 2023 330,531,000 -196,699,000 -145,224,000 1,153,917,000 122,963,000 1,030,954,000 -357,991,000
Dec 2022 108,463,000 -340,744,000 -325,991,000 1,460,242,000 417,812,000 1,042,430,000 -244,716,000

TTM Snapshot

Revenues TTM
$4,826,000
NetIncome TTM
$-442,814,000
OpCashFlow TTM
$0
Assets (Latest)
$1,144,854,000
Forward EPS
$-2.42

Max Pain — expiry 2026-12-18

max pain strike: $15.00 · spot: $20.39 · call oi: 610 · put oi: 1,095
Expected Move to 2026-12-18: ±$5.45 (26.73%) — implied range $14.94 – $25.84 · ATM straddle on $20.00 strike

Peers — same industry

TickerNameMarket CapLastDaily %
TARS Tarsus Pharmaceuticals, Inc. $3.54B $75.69 —
RLAY Relay Therapeutics, Inc. $3.83B $17.47 —
BEAM Beam Therapeutics Inc. $2.51B $24.27 —
MEOBF MESOBLAST LTD $2.47B $1.90 —
ADPT Adaptive Biotechnologies Corp $4.70B $29.43 —

News headlines (Yahoo Finance, 1h cache)

Denali Therapeutics (DNLI) Q2 2026 Earnings Call Transcript
2026-08-13 22:32 · Yahoo
Denali Therapeutics to Report Second Quarter 2026 Financial Results and Business Highlights on August 6, 2026
2026-07-27 20:01 · Yahoo
Denali Therapeutics to Give Opening Plenary Address at Alzheimer’s Association International Conference (AAIC) 2026 and Highlight Breakthroughs in Delivering Biologic Therapies Across Blood-Brain Barr
2026-07-09 20:01 · Yahoo
Denali Therapeutics Enters Agreement to Sell Rare Pediatric Disease Priority Review Voucher for $195 Million
2026-06-18 12:00 · Yahoo
Denali Therapeutics Inc. Q2 2026 Earnings Call Summary
2026-08-07 12:30 · Yahoo
Will Recent Setbacks Impact Growth Prospects of DNLI Stock?
2026-07-15 17:02 · Yahoo
Denali to Sell Priority Review Voucher for $195M Cash Boost
2026-06-19 12:40 · Yahoo
DNLI Stock Gains 33.1% in Three Months: Buy, Sell or Hold the Stock?
2026-08-20 16:20 · Yahoo
Should You Buy, Sell or Hold Biogen Stock After a 9% Rise in a Month?
2026-08-20 14:12 · Yahoo
DNLI Q2 Loss Narrows, Avlayah Sales Drive Strong Launch Momentum
2026-08-07 18:31 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.