FULC — Fulcrum Therapeutics, Inc.

Nasdaq · Health Care · Pharmaceuticals · CIK 1680581 ·
Last close
$3.51
Market Cap
$233.88M
52W High
$8.37
52W Low
$2.83
ADV30
2,548,608
Next earnings
2026-04-27
Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia. The company also discovers programs for the treatment of diamond-blackfan anemia, Bone Marrow Failure Syndromes, novel fetal hemoglobin inducers, fibrotic disorders. It has licensce agreement with CAMP4 which includes certain small molecule compounds, composition of matter and method of use patent rights, and know-how to research, develop, manufacture, use, and commercialize. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 0 -22,186,000 -18,891,000 346,770,000 50,261,000 13,467,000
Dec 2025 0 -22,693,000 -20,334,000 366,284,000 197,533,000 17,284,000
Sep 2025 0 -21,858,000 -19,595,000 214,858,000 47,078,000 16,492,000
Jun 2025 0 -19,815,000 -17,296,000 228,838,000 42,588,000 14,460,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-63,558,000
Investing CF
$-96,714,000
Financing CF
$168,355,000
CapEx
$-488,000
Dividends Paid
Buybacks
EPS Diluted TTM
$-1.15
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-613,169,000
Inventory
Receivables
$1,776,000
ST Investments
$283,055,000
EBIT TTM
$-86,552,000
Pretax Income TTM
$-76,116,000
Interest Exp TTM
Analysts
10

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 0 -84,769,000 -74,880,000 366,284,000 17,284,000 -60,065,000
Dec 2024 80,000,000 -19,834,000 -9,725,000 260,718,000 17,684,000 -2,218,000
Dec 2023 2,805,000 -110,664,000 -97,335,000 257,694,000 22,501,000 -90,965,000
Dec 2022 6,342,000 -112,134,000 -109,871,000 226,685,000 27,743,000 -97,050,000

TTM Snapshot

Revenues TTM
NetIncome TTM
OpCashFlow TTM
Assets (Latest)
Forward EPS
$-0.66

Max Pain — expiry 2026-07-17

max pain strike: $3.00 · spot: $3.46 · call oi: 724 · put oi: 4,569
Expected Move to 2026-07-17: ±$0.46 (13.15%) — implied range $3.01$3.92 · ATM straddle on $3.00 strike

Peers — same industry

TickerNameMarket CapLastDaily %
ACIU AC Immune SA $238.15M $2.34
IFRX InflaRx N.V. $238.61M $1.62
SLGL Sol-Gel Technologies Ltd. $239.57M $73.82
ADAG Adagene Inc. $240.50M $3.64
FHTX Foghorn Therapeutics Inc. $241.31M $4.11

News headlines (Yahoo Finance, 1h cache)

A Look At Fulcrum Therapeutics (FULC) Valuation After Scrapping Lead Sickle Cell Drug And Restructuring
2026-06-05 15:15 · Yahoo
Fulcrum Therapeutics (FULC) Loses 51% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner
2026-06-05 13:35 · Yahoo
FULC Stock Crashes as Cancer Risk Forces Its Only Drug Program's End
2026-06-03 15:00 · Yahoo
Why Did FULC, MVIS, HRTX Stocks Plunge To 52-Week Lows Today?
2026-06-03 03:04 · Yahoo
This Biotech Stock Plunges 54%. Its Sickle Cell Drug Has ‘No Viable Path Forward.’
2026-06-02 16:13 · Yahoo
Meta Platforms upgraded, Okta downgraded: Wall Street's top analyst calls
2026-06-02 13:43 · Yahoo
Fulcrum exploring a potential sale after FDA sidelined its sickle cell drug
2026-06-02 12:08 · Yahoo
FULC Stock Slumps Nearly 50% After Hours As FDA Kills Only Clinical Program Over Cancer Risk
2026-06-01 21:50 · Yahoo
Fulcrum Therapeutics Discontinues Sickle Cell Disease Program After US FDA Raises Malignancy Concerns
2026-06-01 20:56 · Yahoo
Fulcrum Therapeutics Announces Discontinuation of Pociredir Program in Sickle Cell Disease and Initiation of Strategic Review
2026-06-01 20:05 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.