MNPR — Monopar Therapeutics

Nasdaq · Health Care · Pharmaceuticals · CIK 1645469 ·
Last close
$61.47
Market Cap
$411.79M
52W High
$68.79
52W Low
$50.07
ADV30
170,790
Next earnings
2026-08-13
Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the United States. The company develops ALXN1840, a late-stage, investigational once-daily and oral medicine; MNPR-101, a proprietary humanized monoclonal antibody that is conjugated with different radioisotopes for the treatment of advanced solid tumors expressing urokinase plasminogen activator receptor; and MNPR-101-Zr, which is in phase 1 imaging and dosimetry clinical trial, a radiopharmaceutical imaging agent comprised of MNPR-101 conjugated to zirconium-89. It develops MNPR-101-Lu, a Phase1a stage radiotherapeutic comprised of MNPR-101 conjugated to actinium-225. The company has collaborations NorthStar to develop radio-immuno-therapeutics targeting severe COVID-19; Excel Diagnostics and Nuclear Oncology Center, for the investigational imaging agent MNPR-101-Zr and investigational therapeutic agent MNPR-101-Lu; license agreement with Alexion to develop and commercialize ALXN1840, a drug candidate for Wilson disease. The company was founded in 2014 and is headquartered in Wilmette, Illinois.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 0 -5,225,253 -3,893,050 137,983,725 52,544,263 2,589,313
Dec 2025 0 -6,155,228 -5,200,795 140,717,709 61,833,552 2,890,156
Sep 2025 0 -4,093,075 -3,437,601 144,197,278 127,677,360 2,639,430
Jun 2025 0 -3,234,295 -2,453,526 53,865,873 39,501,936 1,663,979

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-10,011,881
Investing CF
$-68,710,838
Financing CF
$91,489,881
CapEx
Dividends Paid
Buybacks
$0
EPS Diluted TTM
$-1.67
As of
2026-06-07

Balance + Analyst (yfinance extras)

Retained Earnings
$-93,402,580
Inventory
Receivables
ST Investments
$84,948,677
EBIT TTM
$-18,707,851
Pretax Income TTM
$-14,984,972
Interest Exp TTM
Analysts
13

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 0 -16,704,415 -13,716,894 140,717,709 2,890,156 -12,201,291
Dec 2024 0 -16,161,721 -15,586,419 60,291,071 5,254,300 -6,404,139
Dec 2023 0 -8,831,235 -8,402,196 7,345,159 1,757,393 -7,858,293
Dec 2022 0 -10,536,877 -10,515,638 13,226,954 3,137,302 -7,228,559

TTM Snapshot

Revenues TTM
NetIncome TTM
OpCashFlow TTM
Assets (Latest)
Forward EPS
$-3.16

Peers — same industry

TickerNameMarket CapLastDaily %
PTCHF PureTech Health plc $413.81M $1.70
CTNM Contineum Therapeutics, Inc. $416.25M $12.72
RZLT Rezolute, Inc. $416.95M $4.33
EPRX EUPRAXIA PHARMACEUTICALS INC. $406.33M $6.22
INDP Indaptus Therapeutics, Inc. $417.86M $3.69

News headlines (Yahoo Finance, 1h cache)

Wall Street Analysts Believe Monopar Therapeutics (MNPR) Could Rally 88.92%: Here's is How to Trade
2026-06-15 13:55 · Yahoo
Monopar Presents Phase 2 ALXN1840 Data Demonstrating Liver Disease Stabilization and Neurologic Improvement in Treatment-Experienced Wilson Disease Patients at EASL 2026
2026-06-01 11:00 · Yahoo
Monopar Announces Publication of Phase 2 Study Demonstrating ALXN1840 Significantly Improves Copper Balance in Patients with Wilson Disease
2026-05-19 21:33 · Yahoo
Monopar Therapeutics Reports First Quarter 2026 Financial Results and Provides Business Updates
2026-05-14 18:00 · Yahoo
Monopar Therapeutics (NASDAQ:MNPR) Is In A Good Position To Deliver On Growth Plans
2026-05-03 13:26 · Yahoo
Monopar Presents Phase 3 Data Showing Greater Neurologic Benefit with ALXN1840 vs SoC in Wilson Disease Patients with Neurologic Symptoms at AAN 2026
2026-04-19 23:00 · Yahoo
Monopar Reports Fourth Quarter and Full-Year 2025 Financial Results and Provides Business Update
2026-03-27 17:00 · Yahoo
Monopar Expands Leadership Team with Appointment of Seasoned Biopharma Executive Susan Rodriguez as Chief Commercial and Strategy Officer
2026-03-02 13:00 · Yahoo
Institutional investors in Monopar Therapeutics Inc. (NASDAQ:MNPR) see US$66m decrease in market cap last week, although long-term gains have benefitted them.
2026-02-11 13:06 · Yahoo
Broadcom Stock Sees Improved Relative Strength Rating
2026-02-09 18:21 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.