OPK — OPKO HEALTH, INC.

Nasdaq · Health Care · Pharmaceuticals · CIK 944809 ·
Last close
$1.42
Market Cap
$1.07B
52W High
$1.55
52W Low
$0.98
ADV30
2,574,797
Next earnings
2026-04-28
OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune system. This segment also engages in the development of Epstein Barr Virus vaccine; Rayaldee, a patented extended-release product for oral administration containing 30 mcg of a prohormone; OPK-88006 oral and injectable product to regulate blood glucose and reduce body weight; NGENLA, recombinant human growth hormone product developed for the long-term treatment of pediatric patients with growth hormone deficiency. The Diagnostics segment offers laboratory testing services, such as detection, diagnosis, evaluation, monitoring, and treatment of diseases, as well as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare under the BioReference brand; and 4Kscore test. OPKO Health, Inc. was founded in 2006 and is headquartered in Miami, Florida.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 124,196,000 45,755,000 -51,017,000 -54,848,000 1,856,796,000 341,881,000 652,186,000
Dec 2025 148,450,000 64,025,000 -38,317,000 -31,257,000 1,931,944,000 369,074,000 663,985,000
Sep 2025 151,669,000 49,893,000 -53,520,000 21,631,000 1,995,508,000 415,198,000 690,018,000
Jun 2025 156,807,000 49,402,000 -59,981,000 -148,441,000 1,972,989,000 271,718,000 676,085,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-163,298,000
Investing CF
$187,968,000
Financing CF
$-119,191,000
CapEx
$-10,917,000
Dividends Paid
Buybacks
$-51,807,000
EPS Diluted TTM
$-0.27
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-2,345,538,000
Inventory
$64,397,000
Receivables
$107,624,000
ST Investments
EBIT TTM
$-125,012,000
Pretax Income TTM
$-228,946,000
Interest Exp TTM
$103,934,000
Analysts
5

Yahoo Snapshot (yfinance, live)

Total Revenue
$581,123,008
EBITDA
$-112,493,000
Free Cash Flow
$-36,094,624
Enterprise Value
$1,137,296,000
Total Cash
$331,862,016
Total Debt
$396,927,008
Shares Out
755,092,256
Trailing EPS
$-0.27
Book Value
$1.59
ROE
-16.9%
ROA
-6.4%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 606,879,000 -225,680,000 1,931,944,000 663,985,000 -178,542,000
Dec 2024 713,142,000 -53,224,000 2,200,212,000 834,764,000 -183,489,000
Dec 2023 863,495,000 -188,863,000 2,011,698,000 622,479,000 -28,197,000
Dec 2022 1,004,196,000 -328,405,000 2,167,259,000 605,611,000 -95,189,000

TTM Snapshot

Revenues TTM
$1,371,868,000
NetIncome TTM
$-64,984,000
OpCashFlow TTM
$0
Assets (Latest)
$2,167,259,000
Forward EPS
$-0.32

Max Pain — expiry 2027-01-15

max pain strike: $1.00 · spot: $1.40 · call oi: 15,780 · put oi: 1,007
Expected Move to 2027-01-15: ±$0.65 (46.43%) — implied range $0.75$2.05 · ATM straddle on $1.50 strike

Peers — same industry

TickerNameMarket CapLastDaily %
SVRA Savara Inc $1.08B $5.26
IVEVF Inventiva S.A. $1.11B $5.33
COLL COLLEGIUM PHARMACEUTICAL, INC $1.12B $34.64
WVE Wave Life Sciences Ltd. $1.13B $5.87
MNKD MANNKIND CORP $1.13B $3.66

News headlines (Yahoo Finance, 1h cache)

Preclinical Data for OPKO Biologics' OPK8801001 in Acromegaly Presented at ENDO 2026
2026-06-15 12:00 · Yahoo
Discover 3 Promising Penny Stocks With Market Caps Over $20M
2026-06-09 12:05 · Yahoo
Assessing OPKO Health (OPK) Valuation After Expanded Nicoya RAYALDEE Partnership In Greater China
2026-06-07 21:19 · Yahoo
How Investors May Respond To OPKO Health (OPK) Boosting Its Nicoya Stake And RAYALDEE Milestones
2026-06-07 03:09 · Yahoo
OPKO Health (OPK) Amends Partnership With Nicoya Therapeutics to Gain Equity Stake
2026-06-05 21:57 · Yahoo
OPKO Health (OPK) Up 17.1% Since Last Earnings Report: Can It Continue?
2026-05-28 15:30 · Yahoo
Here's Why You Should Retain OPK Stock in Your Portfolio for Now
2026-05-21 16:23 · Yahoo
OPKO Health’s ModeX Therapeutics Will Present Data Demonstrating In Vivo CAR-T Cell Generation and Deep B-Cell Depletion in Preclinical Studies
2026-05-12 12:00 · Yahoo
Spotlight On Promising Penny Stocks For May 2026
2026-05-11 18:05 · Yahoo
OPKO Health Expands Nicoya Agreement to Support RAYALDEE® Commercialization in Greater China
2026-04-30 12:30 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.