OPK — OPKO HEALTH, INC.

Nasdaq · Health Care · Pharmaceuticals · CIK 944809 ·
Last close
$1.32
Market Cap
$985.15M
52W High
$1.73
52W Low
$1.08
ADV30
4,415,931
Next earnings
2026-10-28
OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune system. This segment also engages in the development of Epstein Barr Virus vaccine; Rayaldee, a patented extended-release product for oral administration containing 30 mcg of a prohormone; OPK-88006 oral and injectable product to regulate blood glucose and reduce body weight; NGENLA, recombinant human growth hormone product developed for the long-term treatment of pediatric patients with growth hormone deficiency. The Diagnostics segment offers laboratory testing services, such as detection, diagnosis, evaluation, monitoring, and treatment of diseases, as well as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare under the BioReference brand; and 4Kscore test. OPKO Health, Inc. was founded in 2006 and is headquartered in Miami, Florida.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Jun 2026 163,580,000 80,017,000 -25,042,000 -8,416,000 1,829,453,000 300,761,000 645,287,000
Mar 2026 124,196,000 45,755,000 -51,017,000 -54,848,000 1,856,796,000 341,881,000 652,186,000
Dec 2025 148,450,000 64,025,000 -38,317,000 -31,257,000 1,931,944,000 369,074,000 663,985,000
Sep 2025 151,669,000 49,893,000 -53,520,000 21,631,000 1,995,508,000 415,198,000 690,018,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-163,298,000
Investing CF
$187,968,000
Financing CF
$-119,191,000
CapEx
$-10,917,000
Dividends Paid
Buybacks
$-51,807,000
EPS Diluted TTM
$-0.27
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-2,345,538,000
Inventory
$64,397,000
Receivables
$107,624,000
ST Investments
EBIT TTM
$-125,012,000
Pretax Income TTM
$-228,946,000
Interest Exp TTM
$103,934,000
Analysts
5

Yahoo Snapshot (yfinance, live)

Total Revenue
$587,897,024
EBITDA
$-78,172,000
Free Cash Flow
$54,787,376
Enterprise Value
$1,093,670,144
Total Cash
$300,760,992
Total Debt
$398,083,008
Shares Out
746,328,225
Trailing EPS
$-0.07
Book Value
$1.59
ROE
-5.9%
ROA
-5.5%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 606,879,000 -218,985,000 -225,680,000 1,931,944,000 663,985,000 -178,542,000
Dec 2024 713,142,000 -273,558,000 -53,224,000 2,200,212,000 834,764,000 -183,489,000
Dec 2023 863,495,000 -158,057,000 -188,863,000 2,011,698,000 622,479,000 -28,197,000
Dec 2022 1,004,196,000 -246,124,000 -328,405,000 2,167,259,000 605,611,000 -95,189,000

TTM Snapshot

Revenues TTM
$1,371,868,000
NetIncome TTM
$-64,984,000
OpCashFlow TTM
$0
Assets (Latest)
$2,167,259,000
Forward EPS
$-0.28

Max Pain — expiry 2026-09-18

max pain strike: $1.00 · spot: $1.32 · call oi: 5,784 · put oi: 389
Expected Move to 2026-09-18: ±$0.13 (9.85%) — implied range $1.19$1.45 · ATM straddle on $1.50 strike

Peers — same industry

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SDGR Schrodinger, Inc. $992.53M $15.14
OLMA Olema Pharmaceuticals, Inc. $1.00B $11.45
MRVI MARAVAI LIFESCIENCES HOLDINGS, INC. $969.12M $6.57
AVTX Avalo Therapeutics, Inc. $965.48M $18.25
LXRX LEXICON PHARMACEUTICALS, INC. $1.03B $2.31

News headlines (Yahoo Finance, 1h cache)

OPKO Health (OPK) Is Up 36.0% After Narrower Q2 Loss And New 2026 Guidance Has The Bull Case Changed?
2026-07-29 01:10 · Yahoo
Why Opko Health Stock Surged by 33% on Tuesday
2026-07-28 22:06 · Yahoo
OPKO Health Stock Up as Q2 Earnings & Revenues Beat Estimates
2026-07-28 16:55 · Yahoo
OPKO Health, Inc. Q2 2026 Earnings Call Summary
2026-07-28 12:30 · Yahoo
OPKO Health Inc (OPK) Q2 2026 Earnings Call Highlights: Strong Pharmaceutical Growth and ...
2026-07-28 05:01 · Yahoo
OPKO Health Q2 Earnings Call Highlights
2026-07-27 22:02 · Yahoo
Compared to Estimates, OPKO Health (OPK) Q2 Earnings: A Look at Key Metrics
2026-07-27 22:00 · Yahoo
OPKO Health (OPK) Reports Q2 Loss, Tops Revenue Estimates
2026-07-27 21:35 · Yahoo
OPKO Health Reports Second Quarter 2026 Business Highlights and Financial Results
2026-07-27 20:05 · Yahoo
OPKO Health to Report Second Quarter 2026 Financial Results on July 27, 2026
2026-07-23 16:30 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.