SEPN — Septerna, Inc.

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Nasdaq · Health Care · Pharmaceuticals · CIK 1984086 ·
Last close
$37.77
Market Cap
$1.76B
52W High
$51.10
52W Low
$16.65
ADV30
349,460
Next earnings
2026-11-09

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGross profitOp incomeNet incomeAssetsCashLiabilities
Jun 2026 26,746,000 — -16,836,000 -13,034,000 566,737,000 84,662,000 180,016,000
Mar 2026 26,523,000 — -13,300,000 -8,637,000 569,688,000 71,605,000 191,230,000
Dec 2025 24,118,000 — -16,023,000 -10,738,000 596,187,000 120,722,000 214,261,000
Sep 2025 21,495,000 — -9,886,000 8,173,000 606,653,000 319,989,000 217,922,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$107,899,000
Investing CF
$-248,295,000
Financing CF
$1,956,000
CapEx
$-968,000
Dividends Paid
—
Buybacks
$0
EPS Diluted TTM
$-0.81
As of
2026-08-16

Balance + Analyst (yfinance extras)

Retained Earnings
$-175,890,000
Inventory
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Receivables
$14,290,000
ST Investments
$275,796,000
EBIT TTM
$-68,187,000
Pretax Income TTM
$-35,691,000
Interest Exp TTM
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Analysts
9

Yahoo Snapshot (yfinance, live)

Total Revenue
$98,882,000
EBITDA
$-54,395,000
Free Cash Flow
$29,544,876
Enterprise Value
$1,447,752,192
Total Cash
$372,321,984
Total Debt
$22,545,000
Shares Out
46,676,947
Trailing EPS
$-0.53
Book Value
$8.47
ROE
-6.3%
ROA
-7.1%
Div Yield
—

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOp incomeNet incomeAssetsLiabilitiesEquityOp cash flow
Dec 2025 45,951,000 -80,797,000 -48,879,000 596,187,000 214,261,000 381,926,000 110,189,000
Dec 2024 1,075,000 -80,823,000 -71,798,000 456,554,000 36,507,000 420,047,000 -67,470,000
Dec 2023 151,000 -45,550,000 4,180,000 130,867,000 169,241,000 -38,374,000 -38,723,000
Dec 2022 0 -27,967,000 -27,676,000 36,119,000 80,320,000 -44,201,000 -23,303,000

TTM Snapshot

Revenues TTM
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NetIncome TTM
—
OpCashFlow TTM
—
Assets (Latest)
—
Forward EPS
$-1.94

Max Pain — expiry 2027-01-15 (volume-derived — Yahoo OI feed degraded)

max pain strike: $45.00 · spot: $38.92 · call volume: 10 · put volume: 248
Expected Move to 2027-01-15: ±$13.45 (34.56%) — implied range $25.47 – $52.37 · ATM straddle on $39.00 strike

Peers — same industry

TickerNameMarket CapLastDaily %
ZBIO Zenas BioPharma, Inc. $1.76B $26.95 —
XNCR Xencor Inc $1.77B $23.80 —
CMPS COMPASS Pathways plc $1.81B $13.06 —
ANIP ANI PHARMACEUTICALS INC $1.70B $74.00 —
NBTX Nanobiotix S.A. $1.69B $33.31 —

News headlines (Yahoo Finance, 1h cache)

Septerna (SEPN) Heads To Healthcare Conferences, Is The Valuation Already Too Rich?
2026-09-14 14:10 · Yahoo
Septerna, Inc. Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
2026-09-10 20:00 · Yahoo
Septerna Appoints Industry Veteran Rajiv Patni, M.D., as Chief Medical Officer
2026-08-25 12:00 · Yahoo
Septerna, Inc. (SEPN) Reports Q2 Loss, Beats Revenue Estimates
2026-08-10 21:10 · Yahoo
Septerna's Chief People Officer Sold Nearly 12,000 Company Shares. What Does That Mean for Investors?
2026-07-05 13:55 · Yahoo
Is Septerna, Inc. (SEPN) Stock a Biotech Opportunity With a Potential First-in-Class Hypoparathyroidism Treatment?
2026-07-02 19:58 · Yahoo
Is Septerna a Stock to Sell After an Insider Let Go of 15,000 Shares?
2026-06-30 03:25 · Yahoo
Protego Biopharma Appoints Jae B. Kim, MD, as Chief Medical Officer
2026-06-08 11:00 · Yahoo
Party Time: Brokers Just Made Major Increases To Their Septerna, Inc. (NASDAQ:SEPN) Earnings Forecasts
2026-05-17 14:47 · Yahoo
Septerna Highlights Business Progress and Reports First Quarter 2026 Financial Results
2026-05-11 20:01 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.