XENE — Xenon Pharmaceuticals Inc.

Nasdaq · Health Care · Pharmaceuticals · CIK 1582313 · British Columbia, Canada
Last close
$52.40
Market Cap
$5.07B
52W High
$59.99
52W Low
$50.91
ADV30
1,229,470
Next earnings
2026-05-07
Xenon Pharmaceuticals Inc., a neuroscience-focused biopharmaceutical company, engages in the discovery, development, and delivery of therapeutics to treat patients with neurological and psychiatric disorders. Its product candidates include Azetukalner, a novel, potent Kv7 potassium channel opener which is in Phase 3 clinical development for the treatment of epilepsy, including focal onset seizures, and primary generalized tonic-clonic seizures, as well as neuropsychiatric disorders, such as major depressive disorder and bipolar depression. In addition, the company's Phase 1 Single Ascending Dose/Multiple Ascending Dose products include XEN1701 targeting the sodium channel and XEN1120 targeting the Kv7 potassium channel for the treatment of pain. The company has a license and collaboration agreement with Neurocrine Biosciences, Inc. for the development of NBI-921355, a Nav1.2/1.6 sodium channel inhibitor that is in Phase 1 clinical trials for the treatment of certain types of epilepsy. Xenon Pharmaceuticals Inc. was incorporated in 1996 and is headquartered in Burnaby, Canada.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 0 -112,328,000 -102,302,000 1,386,810,000 545,867,000 48,991,000
Dec 2025 0 -109,767,000 -105,261,000 633,163,000 199,163,000 51,403,000
Sep 2025 0 -96,336,000 -90,896,000 607,836,000 104,514,000 48,325,000
Jun 2025 0 -94,229,000 -84,706,000 674,281,000 135,381,000 40,303,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-306,363,000
Investing CF
$-223,794,000
Financing CF
$958,975,000
CapEx
$-889,000
Dividends Paid
Buybacks
EPS Diluted TTM
$-4.70
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-1,347,682,000
Inventory
Receivables
$1,165,000
ST Investments
$548,880,000
EBIT TTM
$-412,660,000
Pretax Income TTM
$-385,147,000
Interest Exp TTM
Analysts
19

Yahoo Snapshot (yfinance, live)

Total Revenue
$0
EBITDA
$-410,188,992
Free Cash Flow
$-186,274,496
Enterprise Value
$3,978,018,816
Total Cash
$1,094,747,008
Total Debt
$7,491,000
Shares Out
96,665,550
Trailing EPS
$-4.70
Book Value
$7.27
ROE
-37.5%
ROA
-24.2%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 7,500,000 -373,070,000 -345,910,000 633,163,000 51,403,000 -279,118,000
Dec 2024 0 -279,298,000 -234,330,000 798,139,000 43,236,000 -181,389,000
Dec 2023 0 -214,054,000 -182,393,000 964,798,000 36,877,000 -151,112,000
Dec 2022 9,434,000 -129,143,000 -125,373,000 754,146,000 32,649,000 -101,028,000

TTM Snapshot

Revenues TTM
NetIncome TTM
OpCashFlow TTM
Assets (Latest)
Forward EPS
$-5.01

Max Pain — expiry 2026-07-17

max pain strike: $55.00 · spot: $52.24 · call oi: 10,888 · put oi: 313
Expected Move to 2026-07-17: ±$7.00 (13.40%) — implied range $45.24$59.24 · ATM straddle on $52.50 strike

Peers — same industry

TickerNameMarket CapLastDaily %
LGND LIGAND PHARMACEUTICALS INC $5.08B $253.25
TVTX Travere Therapeutics, Inc. $5.00B $53.80
AMRX Amneal Pharmaceuticals, Inc. $5.18B $16.24
GRFS Grifols SA $5.19B $7.62
GIKLY Grifols SA $4.81B $5.69

News headlines (Yahoo Finance, 1h cache)

Assessing Xenon Pharmaceuticals (XENE) Valuation After Recent Share Price Pullback And Modest Undervaluation Estimate
2026-06-11 17:11 · Yahoo
UPGUYS Founders Mat Rezaei and Ramin Behzadi Named 2026 EY Entrepreneur Of The Year® Pacific Region Finalists as Canada's Leading TRT Platform Scales Nationwide
2026-06-09 11:30 · Yahoo
Xenon Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
2026-05-29 20:01 · Yahoo
JPMorgan Raises its Price Target on Xenon Pharmaceuticals (XENE)
2026-05-23 02:31 · Yahoo
What to Know About This Fund’s New $22 Million Xenon Pharmaceuticals Buy Ahead of an FDA Filing
2026-05-18 17:44 · Yahoo
SCANBO® FEATURED IN GOVERNMENT OF BRITISH COLUMBIA'S 2026 LIFE SCIENCES ECOSYSTEM MAP
2026-05-12 18:27 · Yahoo
A Look At Xenon Pharmaceuticals (XENE) Valuation After Phase 3 X TOLE2 Success And Extended Cash Runway
2026-05-11 15:13 · Yahoo
Did Positive X-TOLE2 Data and a Major Cash Raise Just Shift Xenon Pharmaceuticals' (XENE) Investment Narrative?
2026-05-11 08:13 · Yahoo
Xenon Pharmaceuticals Q1 Earnings Call Highlights
2026-05-09 08:07 · Yahoo
Xenon Q1 Earnings Match Estimates, Pipeline Development in Focus
2026-05-08 16:47 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.